October 31, 2017

2.8 million TB cases in India, but WHO notes higher funding



At 27.9 lakh, India’s TB incidence in 2016 was down marginally from the previous year’s
 
28.4 lakh. The number of TB-related deaths was 4.35 lakh. down 15% from 5.17 lakh.

tuberculosis, TB cases in India, tuberculosis cases, WHO world health organization, TB

cases, tuberculosis treatment, india news, latest news, indian express, health news India

accounted for 33% of global TB deaths among HIV-negative people, and for 26% of the

combined total of TB deaths in HIV-negative and HIV-positive people.



Following a 2012 decision to mandatorily notify TB cases, India has registered a 37% jump

in cases between 2013-16, shows a new global TB report released by WHO, which also takes

note of the Indian government’s moves towards increased funding for TB elimination.



At 27.9 lakh, India’s TB incidence in 2016 was down marginally from the previous year’s

28.4 lakh. The number of TB-related deaths was 4.35 lakh. down 15% from 5.17 lakh.

India, however, accounted for 33% of global TB deaths among HIV-negative people, and for

26% of the combined total of TB deaths in HIV-negative and HIV-positive people. “An

estimated 10.4 million people fell ill with TB in 2016… 56% were in five countries: India,

Indonesia, China, the Philippines and Pakistan,” the report states. China, India and Indonesia

alone accounted for 45% of global cases in 2016.



The report noted that TB is the ninth leading cause of death worldwide and the leading cause

from a single infectious agent, ranking above HIV/AIDS. “In 2016, there were an estimated

1.3 million TB deaths among HIV-negative people (down from 1.7 million in 2000) and an

additional 374,000 deaths among HIV-positive people,” it states.



On the other hand, the TB mortality rate is falling at about 3% per year worldwide and TB

incidence at about 2% per year; 16% of TB cases die from the disease. Most deaths from TB

could be prevented with early diagnosis and appropriate treatment.



“India is still doing poorly in TB control. At this rate, unless there is serious investment by

the Indian government, we will not eliminate TB by 2025,” said Prof Madhukar Pai, director,

McGill Global Health Programs; and Associate Director, McGill International TB Centre.

Government health authorities, however, stressed that the findings were consistent with

efforts to detect more TB cases. Dr Sunil Khaparde, deputy director general, Central TB

Division, Ministry of Health and Family Welfare, told The Indian Express: “We have started

intervention and early detection programmes due to which the MDR-TB cases have shown a

decline from 1.2 lakh cases in 2015. The number of deaths has also come down,” Dr

Khaparde said.



About India’s increased funding, the reports states: “India stood out as a country in which the

budget envelope for TB was substantially increased in 2017 (to $525 million, almost double

the level of 2016), following political commitment from the Prime Minister to the goal of

ending TB by 2025. The budget is fully funded, including $387 million (74%) from domestic

sources (triple the amount of $124 million in 2016) and the remainder (26%) from

international donor sources,” says the report.



Last February, the government released the National Strategic Plan for Tuberculosis

Elimination 2017-2025 that, while describing TB as India’s “severest health crisis,

emphasised the government’s commitment to end TB in the country by 2030, five years
ahead of the global target of elimination by 2035”.

Source: The Indian Express

October 10, 2017

Japan scientists grow drugs in chicken eggs


Japanese researchers have genetically engineered hens whose eggs contain drugs that can
fight serious diseases including cancer, in a bid to dramatically reduce the cost of treatment, a
report said on Monday .

If the scientists are able to safely produce “interferon beta“, a type of protein used to treat
illnesses including multiple sclerosis and hepatitis, by rearing the hens, the price of the drug -
currently up to 100,000 yen (approx. Rs 58,000) for a few microgrammes -could fall
significantly , said the English edition of the `Yomiuri Shimbun'.

Researchers at the National Institute of Advanced Industrial Science and Technology (AIST)
in the Kansai region kicked off the process by introducing genes that produce interferon beta
into cells that are precursors of chicken sperm, the newspaper reported.

They then used these cells to fertilise eggs and create hens that inherited those genes,
meaning the birds were able to lay eggs containing the disease fighting agent.

The scientists now have three hens whose eggs contain the drug, with the birds laying eggs
almost daily , the report said. The researchers plan to sell the drug to pharmaceutical
companies, halving its price, so the firms can use it first as a research material, the newspaper
said. Consumers may have to wait a while, as Japan has strict regulations concerning the
introduction of new or foreign pharmaceutical products, with screening processes that
routinely take years to complete. But the team hopes that the technological breakthrough will
eventually help drive down the cost of the drug to 10% of its current price, the newspaper
reported. Officials at the institute could not be reached for comment.

 
 
Source: The Times of India