Diabetes is a metabolic disorder that affects several body organs if not taken care of in the initial stages. There are several complications related to diabetes and one of them can be identified by just placing the palm facing each other. A Twitter thread on this condition was initiated by Dr.Akhil Raghavan. Sharing a picture of a patient's hand placed in the same position as described above, the doctor started an insightful thread.
This reveals a condition known as diabetic cheiroarthropathy
Diabetic cheiroarthropathy is a complication associated with
long-term diabetes mellitus. It involves a thickening and tightening of the
skin on the hands, leading to reduced joint mobility. Common manifestations
include stiffness, limited range of motion, and difficulty extending the
fingers. This condition is attributed to the accumulation of advanced glycation
end products (AGEs) in the skin and connective tissues.
Excessive build up on collagen"
Explaining the condition, Dr. Akhil has tweeted: Collagen that has
undergone nonenzymatic glycation becomes excessively cross-linked and resistant
to breakdown, leading to an increased buildup of collagen around joints. In
diabetes, persistent high blood sugar levels lead to increased production of
advanced glycation end products (AGEs). These AGEs contribute to the
cross-linking of collagen fibers in joints, causing stiffness and reduced
flexibility. Over time, this process, known as glycation, results in the
buildup of collagen, contributing to diabetic cheiroarthropathy and
joint-related complications.
Microangiopathy refers to a condition involving the small blood vessels, typically the arterioles and capillaries. It is often associated with chronic diseases like diabetes mellitus and hypertension. In microangiopathy, the small blood vessels undergo structural changes, leading to thickening of vessel walls and narrowing of the lumen. This can result in impaired blood flow to various organs and tissues, causing damage to the affected areas. Common complications include diabetic microangiopathy, affecting the eyes (retinopathy), kidneys (nephropathy), and nerves (neuropathy). Management involves controlling underlying conditions and preventive measures to reduce the risk of complications associated with microvascular damage.
Tight glycemic control, physical therapy, and interventions to improve joint flexibility are essential for managing diabetic cheiroarthropathy. Regular monitoring and comprehensive diabetes care can help mitigate the impact of this condition on hand function in individuals with diabetes.
Other diabetes complications to know
Diabetes can lead to various complications, including neuropathy
(nerve damage), retinopathy (vision impairment), nephropathy (kidney damage),
and cardiovascular issues such as heart disease and stroke. Foot problems,
including ulcers and infections, are common. Uncontrolled diabetes may result
in skin conditions, hearing impairment, and dental issues. Individuals with
diabetes are at a higher risk for infections and slow wound healing.
Furthermore, the condition can contribute to sexual dysfunction and
complications during pregnancy.
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