A new study has found that the composition of the gut microbiome helps in predicting how likely a person will succumb to potentially life-threatening infection with Klebsiella pneumoniae, E.coli and other bugs -- and it may be altered by changing your diet.
Washington [USA], January 12 (ANI): A new
study has found that the composition of the gut microbiome helps in predicting
how likely a person will succumb to potentially life-threatening infection with
Klebsiella pneumoniae, E.coli and other bugs -- and it may be altered by changing
your diet.
The group of bacteria called
Enterobacteriaceae, including Klebsiella pneumoniae, Shigella, E.coli and
others, is present at low levels as part of a healthy human gut microbiome.
However, certain catalytic factors such as increased inflammation in the body,
or by eating contaminated food these bugs can cause illness and disease. In
extreme cases, too much Enterobacteriaceae in the gut can be life-threatening.
Researchers have used computational
approaches including AI to analyse the gut microbiome composition of over
12,000 people across 45 countries from their stool samples. They found that a
person's microbiome 'signature' can predict whether a person's gut is likely to
be colonised by Enterobacteriaceae. The results are consistent across different
states of health and geographic locations.
The researchers identified 135 gut microbe
species that are commonly found in the absence of Enterobacteriaceae. It likely
protects against infection. The results are published in the journal Nature
Microbiology.
Notable among the protective gut species
is a group of bacteria called Faecalibacterium, which produces beneficial
compounds called short-chain fatty acids by breaking down fibre in the foods we
eat.
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