People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalized from a heart attack or heart failure, regardless of their body mass index, according to new research.
Washington DC [India], January 22
(ANI): People with pockets of fat hidden inside their muscles are at a higher
risk of dying or being hospitalized from a heart attack or heart failure,
regardless of their body mass index, according to new research.
This is the first study to
comprehensively investigate the effects of fatty muscles on heart disease. The
new finding adds evidence that existing measures, such as body mass index or
waist circumference, are not adequate to evaluate the risk of heart disease
accurately for all people.
The new study was led by Professor
Viviany Taqueti, Director of the Cardiac Stress Laboratory at Brigham and
Women's Hospital and Faculty at Harvard Medical School, Boston, USA.
She said: "Obesity is now one of
the biggest global threats to cardiovascular health, yet body mass index -- our
main metric for defining obesity and thresholds for intervention -- remains a
controversial and flawed marker of cardiovascular prognosis. This is especially
true in women, where high body mass index may reflect more 'benign' types of
fat.
"Intermuscular fat can be found
in most muscles in the body, but the amount of fat can vary widely between
different people. In our research, we analyse muscle and different types of fat
to understand how body composition can influence the small blood vessels or
'microcirculation' of the heart, as well as future risk of heart failure, heart
attack and death."
The new research included 669 people
who were being evaluated at the Brigham and Women's Hospital for chest pain
and/or shortness of breath and found to have no evidence of obstructive
coronary artery disease.
Patients were followed up for around
six years and researchers recorded whether any patients died or were
hospitalised for a heart attack or heart failure.
Researchers found that people with
higher amounts of fat stored in their muscles were more likely to have damage
to the tiny blood vessels that serve the heart (coronary microvascular
dysfunction or CMD), and they were more likely to go on to die or be
hospitalised for heart disease. (ANI)
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