July 11, 2025

WHO launches guidelines for clinical management of dengue, chikungunya, Zika & yellow fever

The WHO has introduced its first clinical guidelines for managing dengue, chikungunya, Zika, and yellow fever. These diseases, spread by Aedes mosquitoes, now threaten over 5.6 billion people globally. The guidelines aim to improve diagnosis and treatment amid symptom overlaps and limited testing. They provide evidence-based care strategies for healthcare providers at all levels.

"Clinicians must recognize these diseases and treat patients according to the latest, evidence-based guidance." – WHO

In a first, the World Health Organization (WHO) has published guidelines for the clinical management of patients with suspected or confirmed arboviral diseases, such as dengue, chikungunya, Zika, and yellow fever.

Key Points

1 WHO addresses overlapping symptoms of arboviruses complicating diagnosis

2 Guidelines cover fluid management and adjunct therapies for yellow fever

3 Aedes mosquito spread increases outbreak risks due to climate change

4 Recommendations apply to all healthcare levels from clinics to hospitals

Arboviruses have become a growing public health threat, putting over 5.6 billion people at risk. Once limited to tropical and subtropical climates, the Aedes mosquitoes that transmit these diseases are spreading to new regions due to climate change, population growth, increased travel, and urbanisation, increasing the risk of outbreaks.

While early detection and treatment are key for better outcomes, diagnosing these diseases "can be challenging as their symptoms often overlap and resemble other febrile illnesses," said the WHO.

"In addition, in some regions, multiple arboviruses may circulate at the same time, making clinical diagnosis even more challenging, especially where testing is limited,” the WHO added.

The global health body launched the new guidelines while stressing the need for "clinicians to recognise these diseases and treat patients according to the latest, evidence-based guidance”.

Designed to help healthcare providers, the guidelines will help them give patients the best possible care to prevent severe disease and death.

It includes recommendations to healthcare providers for the management of patients with both non-serious and serious arboviral illnesses requiring hospitalisation.

The guideline can be applied at all levels of the health system, including community-based care, primary care, emergency departments, and hospital wards.

It also provides recommendations on treatment the choice of fluid management and measurements to guide fluid administration; and treatment with adjunctive therapies for patients with yellow fever.

“The guideline will also serve as a reference source for policymakers, health managers, and health facility administrators to support the development of national, regional, and local guidelines for epidemic and pandemic preparedness,” the WHO said.

https://www.newkerala.com/news/o/launches-guidelines-clinical-management-dengue-chikungunya-zika-yellow-fever-144

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