21 October, 2016
A study conducted by Indian-origin researcher found that elevated levels of 'stress hormone'
cortisol measured in hair can predict success rate of conceiving through In Vitro
Fertilisation (IVF). The findings suggests that the levels of a hormone when measured
in hair can significantly predict the likelihood of pregnancy in women undergoing IVF treatment.
cortisol measured in hair can predict success rate of conceiving through In Vitro
Fertilisation (IVF). The findings suggests that the levels of a hormone when measured
in hair can significantly predict the likelihood of pregnancy in women undergoing IVF treatment.
The study was published in the journal Psychoneuroendocrinology.
This technique provides more reliable measure of hormonal function compared to
other techniques using saliva, blood and urine that measure only short term levels of
the hormone.
other techniques using saliva, blood and urine that measure only short term levels of
the hormone.
The study provide the first proper evidence that long-term levels of cortisol, which are
affected by many lifestyle factors including diet, exercise, caffeine and most notably
stress, may play an important role in determining reproductive outcomes.
affected by many lifestyle factors including diet, exercise, caffeine and most notably
stress, may play an important role in determining reproductive outcomes.
A total of 135 women were observed for the study, 60 percent of whom became pregnant
following IVF treatment. Eighty eight women provided hair samples and the rest submitted
salivary samples for the measurement of cortisol. After analysing both types of cortisol
data, researchers found that short-term salivary cortisol measurements were not
related to pregnancy but in contrast the hair cortisol concentrations were.
following IVF treatment. Eighty eight women provided hair samples and the rest submitted
salivary samples for the measurement of cortisol. After analysing both types of cortisol
data, researchers found that short-term salivary cortisol measurements were not
related to pregnancy but in contrast the hair cortisol concentrations were.
The findings suggest that 27 percent of the variance in pregnancy outcome was
accounted for by hair cortisol concentrations after controlling for other known factors that
are linked to IVF success such as age, body mass index (BMI), number of eggs retrieved
and the number of eggs fertilised.
accounted for by hair cortisol concentrations after controlling for other known factors that
are linked to IVF success such as age, body mass index (BMI), number of eggs retrieved
and the number of eggs fertilised.
"Researchers have been interested in the role that cortisol may play in determining
reproductive outcomes for some time now, not least because cortisol is typically elevated
in relation to stress," said lead researcher Kavita Vedhara, Professor at the University of
Nottingham School of Medicine.
reproductive outcomes for some time now, not least because cortisol is typically elevated
in relation to stress," said lead researcher Kavita Vedhara, Professor at the University of
Nottingham School of Medicine.
"While these results do not specifically implicate stress, they do provide preliminary
evidence that long-term cortisol levels are associated with a reduced likelihood of
conceiving. A range of factors are likely to account for that, stress being one
possibility," Vedhara added.
evidence that long-term cortisol levels are associated with a reduced likelihood of
conceiving. A range of factors are likely to account for that, stress being one
possibility," Vedhara added.
Source: www.zeenews.india.com
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