June 02, 2023

How the wrinkles of the brain impact its function: Study

From understanding how the brain functions to the comparisons between the cerebral surface and

the connectome, here's what you need to know.

The shape of the brain and its wrinkles that contribute to the walnut appearance of the brain impacts

the way it works. In a study titled 'Geometric constraints on human brain function,’ the researchers

compared the two main components of the brain's structure – the outer folds of the cerebral cortex

and the web of nerves that connect the significant regions of the cerebral cortex. Speaking to a

publication, James Pang, co-author of the article and physicist at Monash University in Melbourne,

Australia said that they used concepts from physics and engineering to explore how anatomy

impact function. The study further explored that the shape of the cerebral cortex had more impact

than the connectome.

How the wrinkles of the brain impact its function: Study(Unsplash)

Understanding how the brain functions

In order to understand how the brain works when the neurons are excited, the researchers tried to

include mathematical theory of waves. According to neuroscientists who have studied the

mechanism of neurons and their ways of sending messages to the brain through decades – the

neurons, when excited can send messages to other neurons. The neurons in the cerebral cortex can

communicate their state of excitement to their neighboring regions. However. Each neuron has a

long filament called axon that also helps in sending messages to distant brain cells.

The study of vibration

The brain's neuronal excitement can come in waves and spread to various parts of the brain, and

travel back in periodic oscillations. The researchers studied the modes by which the brainwaves

propagate at the cortical surface and at the connectome. Then they studied the information gathered

from MRI that images the activity of the brain supported by blood flow. The researchers further

analysed the information and came to the conclusion that the brainwave modes were better

explained by the surface geometry than by the connectome. For the study, the authors used an ideal

brain structure – however, the walnut-shaped convulsions of the cortex are known to vary in shape

and size from person to person.

https://www.hindustantimes.com/lifestyle/health/how-the-wrinkles-of-the-brain-impact-itsfunction-

study-101685625338724.html

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