Study reveals presence of specific lipids that can help decrease tissue ageing
Exercise can help stop the build-up of lipids—a type of fat that
accumulates as the body’s tissue gets older—and thus aid in reversing ageing,
revealed a study Friday.
A team of scientists from Amsterdam University Medical Center
(UMC), in the Netherlands, conducted the study on both humans and mice.
Their results, published in the journal Nature Aging, revealed the
presence of specific lipids that indicate tissue ageing and which can be
decreased through exercise.
“The idea that we could reverse ageing is something that was long
considered science fiction, but these findings do allow us to understand a lot
more about the ageing process,” said Riekelt Houtkooper, Professor at the
laboratory Genetic Metabolic Diseases of Amsterdam UMC.
“Everyone says that ‘it’s just part of getting older,’ but this
doesn’t actually have to be true. By understanding more about the ageing
process, we can also look into new ways of intervening,” added Georges
Janssens, Assistant professor at Amsterdam UMC.
For the study in mice, the team investigated how the composition
of fats caused changes in muscles, kidneys, liver, and heart.
They found a type of lipid, the bis (monoacylglycero) phosphates
(or BMPs), were elevated in all tissues from the older animals.
The team also found a similar accumulation of BMP in muscle
biopsies of older adults. But biopsies after one hour of exercise daily
revealed a decrease in the level of BMPs, stressing the importance of exercise.
However, further studies are needed to ascertain the role of
physical activity in reversing the process of ageing, the team said.
https://www.tribuneindia.com/news/health/scientists-decode-how-exercise-can-reverse-ageing-610137
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